For medium-risk sterile compounding, what is the acceptable refrigerator storage duration?

For medium-risk sterile compounding, the acceptable storage duration in a refrigerator is 9 days, which aligns with the guidelines set forth in the United States Pharmacopeia (USP) standards. These guidelines indicate that medium-risk preparations can be stored for 9 days at controlled cold temperatures (typically between 2°C and 8°C) when properly sealed and refrigerated.

This time frame is essential to ensure the quality and safety of the compounded sterile preparations, considering potential microbial contamination and degradation of the products over time. During this period, the compounded medications remain effective and safe for patient use, provided they are handled correctly, including maintaining appropriate environmental conditions during storage.

Understanding these standards is crucial for pharmacy practice, as it helps ensure patient safety through proper medication management and adherence to compounding regulations.